Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | GLA | P06280 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | GALR3 | O60755 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 2/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701530 | 0.84 | KDM4E (0.65) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701665 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL7649493 | 0.80 | KDM4E (0.56) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701575 | 0.78 | MDM2 (0.59) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL4474609 | 0.78 | MDM2 (0.62) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9526447 | 0.78 | GAA (1.00) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL7371748 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9701620 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL9526262 | 0.78 | ALDH1A1 (0.67) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL7371751 | 0.78 | KDM4E (0.57) | KDM4EALDH1A1GAAGLAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550576-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992006085-A1 | PHENYLPYRIDINOL DERIVATIVES AS MEDICAMENTS | SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-04-16 | — | — | WO | disclosed |