Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 19/20 | 0.57 |
| ▸ | CA2 | P00918 | 19/20 | 0.57 |
| ▸ | CA4 | P22748 | 19/20 | 0.57 |
| ▸ | CA6 | P23280 | 19/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530863 | 0.82 | KDM4E (0.49) | CA1CA2CA4CA6 | |
| SCHEMBL9526738 | 0.82 | DAO (0.41) | CA1CA2CA4CA6 | |
| SCHEMBL8946555 | 0.81 | CA1 (0.60) | CA1CA2CA4CA6AURKA | |
| SCHEMBL9526845 | 0.79 | ADORA3 (0.40) | CA1CA2CA4CA6AURKA | |
| SCHEMBL20165853 | 0.79 | CA1 (0.59) | CA1CA2CA4CA6AURKA | |
| SCHEMBL9526939 | 0.79 | CA1 (0.60) | CA1CA2CA4CA6AURKA | |
| SCHEMBL17963741 | 0.74 | CA1 (0.67) | CA1CA2CA4CA6AURKA | |
| SCHEMBL9526780 | 0.70 | DAO (0.41) | CA1CA2CA4CA6 | |
| SCHEMBL9527328 | 0.69 | CA1 (0.50) | CA1CA2CA4CA6 | |
| SCHEMBL9530865 | 0.69 | CA1 (0.50) | CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62056471-A | — | — | None | — | — | JP | disclosed |
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| WO-1990015800-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |
| JP-S6256471-A | NITROGEN-CONTAINING TETRACYCLIC COMPOUND | TEIKOKU HORMONE MFG CO LTD | 1987-03-12 | — | — | JP | disclosed |