Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 4/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.38 |
| ▸ | CMA1 | P23946 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 8/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527790 | 0.85 | TACR3 (0.41) | TACR3PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL9529074 | 0.84 | NCEH1 (0.43) | TACR3POLBGPR88CACNA2D1FAAH | |
| SCHEMBL9528534 | 0.84 | TACR3 (0.42) | TACR3POLBGPR88CACNA2D1CYP1A2 | |
| SCHEMBL9528223 | 0.83 | TACR3 (0.41) | TACR3PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL9528353 | 0.82 | TACR3 (0.41) | TACR3CACNA2D1 | |
| SCHEMBL9528466 | 0.82 | TACR3 (0.41) | TACR3CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL9527611 | 0.82 | TACR3 (0.41) | TACR3PRSS1CTSGCTRB1CMA1 | |
| SCHEMBL9528447 | 0.82 | TACR3 (0.38) | TACR3POLBCTSKGPR88CACNA2D1 | |
| SCHEMBL9527591 | 0.81 | FAAH (0.42) | TACR3GPR88FAAH | |
| SCHEMBL9527595 | 0.81 | NCEH1 (0.42) | TACR3POLBGPR88CACNA2D1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319170-B1 | ACYL DERIVATIVES OF HYDROXY PYRIMIDINES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | claimed |