Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.37 |
| ▸ | CMA1 | P23946 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527611 | 0.97 | TACR3 (0.41) | TACR3PKMCCNE1CDK2LMNA | |
| SCHEMBL9529074 | 0.85 | NCEH1 (0.43) | TACR3POLBGPR88ALDH1A1CACNA2D1 | |
| SCHEMBL9527699 | 0.85 | TACR3 (0.40) | TACR3POLBGPR88CACNA2D1PRSS1 | |
| SCHEMBL9528534 | 0.85 | TACR3 (0.42) | TACR3POLBGPR88LMNACACNA2D1 | |
| SCHEMBL9528680 | 0.85 | TACR3 (0.41) | TACR3LMNAALDH1A1CACNA2D1PRSS1 | |
| SCHEMBL9527618 | 0.84 | PKM (0.38) | PKMPOLBCCNE1CDK2LMNA | |
| SCHEMBL9528223 | 0.84 | TACR3 (0.41) | TACR3POLBGPR88LMNACACNA2D1 | |
| SCHEMBL9528466 | 0.83 | TACR3 (0.41) | TACR3ALDH1A1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL9528353 | 0.83 | TACR3 (0.41) | TACR3LMNACACNA2D1KMT2A | |
| SCHEMBL9528447 | 0.83 | TACR3 (0.38) | TACR3POLBGPR88ALDH1A1CACNA2D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0319170-B1 | ACYL DERIVATIVES OF HYDROXY PYRIMIDINES | PFIZER INC. (US) | 1993-03-17 | — | — | EP | claimed |