Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | ILK | Q13418 | 1/20 | 0.34 |
| ▸ | UBE2M | P61081 | 3/20 | 0.34 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 2/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335151 | 0.73 | CHRNB4 (0.42) | DYRK1APDE10AHCRTR1P2RY2UBE2M | |
| SCHEMBL9531311 | 0.66 | PTGS1 (0.35) | DYRK1APDE10AHCRTR1P2RY2AHR | |
| SCHEMBL9531314 | 0.66 | AHR (0.33) | DYRK1APDE10AHCRTR1P2RY2ILK | |
| SCHEMBL1319670 | 0.63 | SMN1; SMN2 (0.57) | DYRK1AILKALDH1A1GAAAHR | |
| SCHEMBL30421999 | 0.63 | SMN1; SMN2 (0.57) | DYRK1AILKALDH1A1GAAAHR | |
| SCHEMBL7516969 | 0.63 | NPC1 (0.45) | DYRK1APDE10AILKUBE2MDCUN1D1 | |
| SCHEMBL7967354 | 0.62 | NPC1 (0.68) | DYRK1AUBE2MDCUN1D1ALDH1A1GAA | |
| SCHEMBL18711260 | 0.61 | UBE2M (0.60) | DYRK1AUBE2MDCUN1D1ALDH1A1GAA | |
| SCHEMBL24233849 | 0.61 | UBE2M (0.39) | DYRK1AILKUBE2MDCUN1D1ALDH1A1 | |
| Phosphoric Acid SCHEMBL6886618 | 0.60 | P2RY2 (0.59) | DYRK1AHCRTR1P2RY2UBE2MDCUN1D1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |