Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9335151 | 0.81 | CHRNB4 (0.42) | PTGS1PTGS2P2RY2CYSLTR1HCRTR1 | |
| SCHEMBL9339059 | 0.74 | KAT8 (0.46) | PTGS1PTGS2CYSLTR1CYSLTR2PTGER4 | |
| SCHEMBL9531314 | 0.74 | AHR (0.33) | P2RY2HCRTR1BACE1AHRPDE10A | |
| SCHEMBL9339062 | 0.73 | CYSLTR1 (0.38) | PTGS1PTGS2CYSLTR1CYSLTR2PTGER4 | |
| SCHEMBL9527837 | 0.66 | DYRK1A (0.38) | P2RY2HCRTR1AHRPDE10ADYRK1A | |
| SCHEMBL1121430 | 0.62 | IDO1 (0.50) | — | |
| SCHEMBL11942311 | 0.61 | IDO1 (0.38) | — | |
| SCHEMBL840465 | 0.61 | GABRA1 (0.45) | BACE1 | |
| SCHEMBL4104243 | 0.61 | CCR5 (0.57) | — | |
| SCHEMBL9339029 | 0.61 | PTGER4 (0.55) | PTGS1PTGS2CYSLTR1CYSLTR2PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |