Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | ILK | Q13418 | 2/20 | 0.30 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531311 | 0.74 | PTGS1 (0.35) | AHRHCRTR1P2RY2BACE1PDE10A | |
| SCHEMBL9335151 | 0.72 | CHRNB4 (0.42) | HCRTR1P2RY2BACE1PDE10ADYRK1A | |
| SCHEMBL9527837 | 0.66 | DYRK1A (0.38) | AHRHCRTR1P2RY2PDE10ADYRK1A | |
| SCHEMBL7310726 | 0.60 | IDO1 (0.39) | — | |
| SCHEMBL840464 | 0.60 | ADRB1 (0.45) | — | |
| SCHEMBL631423 | 0.60 | CYP3A4 (0.35) | — | |
| SCHEMBL7124643 | 0.59 | SLC6A2 (0.32) | — | |
| Bromide SCHEMBL8106423 | 0.58 | UBE2M (0.38) | DYRK1A | |
| SCHEMBL4380249 | 0.57 | PNMT (0.36) | — | |
| SCHEMBL481290 | 0.57 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533695-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. | PFIZER (US) | 1993-03-31 | — | — | EP | disclosed |
| WO-1991017163-A1 | IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1991-11-14 | — | — | WO | disclosed |