Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CXCR2 | P25025 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | CMA1 | P23946 | 1/20 | 0.40 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055700 | 0.69 | MEN1 (0.60) | LMNATP53MDM2MEN1KMT2A | |
| SCHEMBL13495124 | 0.69 | DAO (0.53) | DAOLMNAMEN1KMT2A | |
| SCHEMBL7656605 | 0.67 | CXCR2 (0.67) | DAOCXCR2 | |
| SCHEMBL6502344 | 0.67 | ALDH1A1 (0.51) | LMNA | |
| SCHEMBL14407557 | 0.65 | PDE4A (0.68) | LMNANPC1RAB9ATP53MDM2 | |
| SCHEMBL21055329 | 0.65 | MEN1 (0.51) | DAOLMNACXCR2F2PLG | |
| SCHEMBL18324390 | 0.64 | NPSR1 (0.53) | DAOLMNACXCR2NPC1RAB9A | |
| SCHEMBL4741835 | 0.64 | LMNA (0.51) | LMNATP53MDM2MEN1KMT2A | |
| SCHEMBL196531 | 0.63 | F2 (0.54) | DAOLMNAF2PLGELANE | |
| SCHEMBL4699093 | 0.63 | DAO (0.46) | DAOF2PLGELANECTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0531382-A1 | N-SUBSTITUTED-1,2,4-TRIAZOLONE COMPOUNDS FOR TREATMENT OF CARDIOVASCULAR DISORDERS | G.D. SEARLE & CO. (US) | 1993-03-17 | — | — | EP | disclosed |