Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 7/20 | 0.41 |
| ▸ | CA2 | P00918 | 7/20 | 0.41 |
| ▸ | CA4 | P22748 | 7/20 | 0.41 |
| ▸ | CA6 | P23280 | 7/20 | 0.41 |
| ▸ | DRD2 | P14416 | 4/20 | 0.40 |
| ▸ | DRD1 | P21728 | 4/20 | 0.40 |
| ▸ | DRD5 | P21918 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528450 | 0.81 | CA1 (0.41) | CA1CA2CA4CA6DRD2 | |
| SCHEMBL9526738 | 0.81 | DAO (0.41) | DAODDOCA1CA2CA4 | |
| SCHEMBL9526939 | 0.81 | CA1 (0.60) | CA1CA2CA4CA6 | |
| SCHEMBL9526776 | 0.71 | ADORA3 (0.43) | CA1CA2CA4CA6DRD2 | |
| SCHEMBL9528165 | 0.70 | CA1 (0.57) | CA1CA2CA4CA6 | |
| SCHEMBL9528233 | 0.69 | ALDH1A1 (0.32) | CA1CA2CA4CA6DRD2 | |
| SCHEMBL8946370 | 0.68 | KIF11 (0.53) | CA1CA2CA4CA6DRD2 | |
| SCHEMBL29370154 | 0.67 | CA1 (0.56) | CA1CA2CA4CA6DRD2 | |
| SCHEMBL4374361 | 0.67 | CA1 (0.56) | CA1CA2CA4CA6DRD2 | |
| SCHEMBL29962984 | 0.66 | CA1 (0.57) | CA1CA2CA4CA6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |