Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN5 | P54829 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 9/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9528877 | 0.93 | KMT2A (0.36) | KMT2AALDH1A1MEN1HPGDTLR9 | |
| SCHEMBL9528727 | 0.85 | CYSLTR2 (0.42) | KMT2AMEN1CNR1 | |
| SCHEMBL9526764 | 0.85 | NPC1 (0.37) | KDM4EROCK2 | |
| SCHEMBL9531910 | 0.84 | PLA2G4A (0.41) | KMT2AMEN1CNR1 | |
| SCHEMBL9526686 | 0.78 | NPC1 (0.36) | ALDH1A1ROCK2 | |
| SCHEMBL9526859 | 0.78 | B3GAT3 (0.36) | HPGDROCK2 | |
| SCHEMBL9526830 | 0.76 | NPC1 (0.35) | ROCK2 | |
| SCHEMBL9490190 | 0.74 | MAPT (0.41) | PTPN5KMT2AALDH1A1MEN1TLR8 | |
| SCHEMBL9488311 | 0.74 | ACACB (0.37) | PTPN5HPGDTLR9TLR8TLR7 | |
| SCHEMBL9527469 | 0.74 | NPC1 (0.35) | KDM4EROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337767-B1 | CYCLIC AMIDES | ICI AMERICAS INC. (US) | 1993-01-13 | — | — | EP | disclosed |
| US-5047402-A | Leukotriene Antagonists | ICI AMERICAS INC. (US) | 1991-09-10 | — | — | US | disclosed |
| EP-0337767-A1 | Cyclic amides | ICI AMERICAS INC. (US) | 1989-10-18 | — | — | EP | disclosed |