Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7174186 | 0.81 | PTPN1 (0.46) | SMN1; SMN2TAS1R3TAS1R1TAS1R2POLB | |
| SCHEMBL9031190 | 0.79 | ALDH1A1 (0.49) | MAPK1HSD17B10SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL231486 | 0.78 | KDM4E (0.51) | USP2MAPK1HSD17B10SMN1; SMN2ADORA3 | |
| SCHEMBL7959792 | 0.78 | MAPT (0.50) | USP2MAPK1HSD17B10SMN1; SMN2ADORA3 | |
| SCHEMBL9031311 | 0.78 | HPGD (0.62) | USP2MAPK1HSD17B10SMN1; SMN2ADORA3 | |
| SCHEMBL21807185 | 0.78 | USP2 (0.46) | USP2MAPK1HSD17B10SMN1; SMN2ADORA3 | |
| SCHEMBL7264596 | 0.78 | KMT2A (0.54) | HSD17B10SMN1; SMN2ALDH1A1LMNAPOLB | |
| SCHEMBL8794840 | 0.78 | LMNA (0.54) | HSD17B10ALDH1A1CYP1A2KDM4ELMNA | |
| SCHEMBL20194511 | 0.77 | ALDH1A1 (0.53) | USP2MAPK1HSD17B10SMN1; SMN2ADORA3 | |
| SCHEMBL7035785 | 0.77 | HSD17B1 (0.56) | SMN1; SMN2ALDH1A1LMNAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0523046-A1 | 2-ANILINO PHENYLACETIC ACID DERIVATIVES AS INHIBITORS OF PLA 2? AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-01-20 | — | — | EP | disclosed |
| US-5159085-A | Antiinflammatory, antiallergens, cytoprotective agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-27 | — | — | US | disclosed |
| US-5021576-A | Antiinflammatory, antiarthritic, hypotensive, anticarcinogenic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-04 | — | — | US | disclosed |
| WO-1991006539-A1 | 2-ANILINO PHENYLACETIC ACID DERIVATIVES AS INHIBITORS OF PLA2 AND LIPOXYGENASE | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-05-16 | — | — | WO | disclosed |