Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530604 | 0.77 | EPHX1 (0.42) | EPHX2PGREPHX1ABCC9KCNJ11 | |
| SCHEMBL10453855 | 0.76 | EPHX1 (0.50) | EPHX2EPHX1ABCC9KCNJ11NPC1 | |
| SCHEMBL10453589 | 0.76 | EPHX1 (0.50) | EPHX2EPHX1ABCC9KCNJ11NPC1 | |
| SCHEMBL9528819 | 0.76 | EPHX1 (0.50) | EPHX2EPHX1ABCC9KCNJ11NPC1 | |
| SCHEMBL9529344 | 0.76 | EPHX1 (0.50) | EPHX2EPHX1ABCC9KCNJ11NPC1 | |
| SCHEMBL9528719 | 0.74 | PKM (0.39) | EPHX2EPHX1ABCC9KCNJ11MAPT | |
| SCHEMBL9529412 | 0.73 | HSD17B10 (0.40) | EPHX2SIGMAR1NPC1RAB9AGRIN2D | |
| SCHEMBL10453334 | 0.72 | P2RX7 (0.48) | EPHX2SIGMAR1PGRABCC9KCNJ11 | |
| SCHEMBL9529175 | 0.72 | NAMPT (0.45) | EPHX1ABCC9KCNJ11MEN1KMT2A | |
| SCHEMBL9529457 | 0.72 | ABCC9 (0.46) | ABCC9KCNJ11RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |