Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | ABCC9 | O60706 | 4/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 4/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10453855 | 0.81 | EPHX1 (0.50) | EPHX1PAX8DGAT1EPHX2SAE1 | |
| SCHEMBL10453589 | 0.81 | EPHX1 (0.50) | EPHX1PAX8DGAT1EPHX2SAE1 | |
| SCHEMBL9528819 | 0.81 | EPHX1 (0.50) | EPHX1PAX8DGAT1EPHX2SAE1 | |
| SCHEMBL9529344 | 0.81 | EPHX1 (0.50) | EPHX1PAX8DGAT1EPHX2SAE1 | |
| SCHEMBL9529415 | 0.77 | EPHX2 (0.44) | EPHX1PAX8EPHX2ABCC9KCNJ11 | |
| SCHEMBL9528719 | 0.73 | PKM (0.39) | EPHX1PAX8EPHX2ABCC9KCNJ11 | |
| SCHEMBL9527776 | 0.72 | EPHX1 (0.47) | EPHX1PAX8SAE1UBA2ABCC9 | |
| SCHEMBL10452542 | 0.72 | EPHX1 (0.47) | EPHX1PAX8SAE1UBA2ABCC9 | |
| SCHEMBL9529175 | 0.71 | NAMPT (0.45) | EPHX1PAX8ABCC9KCNJ11IDO1 | |
| SCHEMBL9529457 | 0.71 | ABCC9 (0.46) | SAE1UBA2ABCC9KCNJ11DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |