Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28161278 | 0.83 | PARP1 (0.41) | APLNRHTTPARP1KDM4ELMNA | |
| SCHEMBL9512926 | 0.83 | HPGD (0.41) | APLNRHTTPARP1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL9267601 | 0.80 | PARP1 (0.39) | APLNRHTTPARP1ALDH1A1KDM4E | |
| SCHEMBL8954337 | 0.78 | EPHX2 (0.38) | APLNRALOX5HTTPARP1PTGES | |
| SCHEMBL9212125 | 0.72 | ALDH1A1 (0.36) | PARP1ALDH1A1MAPTMAPK1 | |
| SCHEMBL10005229 | 0.71 | KDM4E (0.48) | ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9529092 | 0.71 | PARP1 (0.35) | PARP1 | |
| SCHEMBL8957092 | 0.71 | ALDH1A1 (0.39) | PARP1ALDH1A1MAPTMAPK1 | |
| SCHEMBL8741912 | 0.70 | AGTR1 (0.36) | APLNRPARP1 | |
| SCHEMBL672823 | 0.69 | ALOX5 (0.44) | ALOX5HTTPTGESALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561895-A1 | USE OF ANGIOTENSIN II RECEPTOR ANTAGONISTS IN THE PREVENTION OF RESTINOSIS | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |