Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | APLNR | P35414 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9267601 | 0.87 | PARP1 (0.39) | HPGDAPLNRPARP1MAPTHTT | |
| SCHEMBL28161278 | 0.85 | PARP1 (0.41) | APLNRPARP1MAPTHTTKDM4E | |
| SCHEMBL9509544 | 0.83 | APLNR (0.40) | APLNRPARP1MAPTHTTKDM4E | |
| SCHEMBL4356446 | 0.77 | ALDH1A1 (0.42) | HPGDPARP1 | |
| SCHEMBL8954337 | 0.76 | EPHX2 (0.38) | HPGDAPLNRPARP1HTT | |
| SCHEMBL225 | 0.73 | ALDH1A1 (0.41) | PARP1KDM4E | |
| SCHEMBL9081675 | 0.73 | GPR84 (0.45) | HPGD | |
| SCHEMBL9529092 | 0.73 | PARP1 (0.35) | PARP1 | |
| SCHEMBL7610834 | 0.72 | HPGD (0.40) | HPGDPARP1MAPTHTTKDM4E | |
| SCHEMBL9082364 | 0.71 | GPR84 (0.46) | HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0561979-A1 | USE OF ANGIOTENSIN II ANTAGONISTS IN THE TREATMENT OF ANGINA PECTORIS | SMITHKLINE BEECHAM PLC (GB) | 1993-09-29 | — | — | EP | disclosed |