Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 2/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532029 | 0.85 | KDM4E (0.42) | KDM4ELMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL9530012 | 0.83 | KDM4E (0.42) | KDM4ELMNAHTTSMN1; SMN2GAA | |
| SCHEMBL9529021 | 0.83 | SMN1; SMN2 (0.37) | KDM4EHKDC1LMNAHTTSMN1; SMN2 | |
| SCHEMBL23366565 | 0.82 | KDM4E (0.49) | KDM4ELMNAHTTSMN1; SMN2GAA | |
| SCHEMBL9529276 | 0.81 | ALDH1A1 (0.46) | KDM4ELMNAHTTNPC1RAB9A | |
| SCHEMBL9532053 | 0.81 | NPC1 (0.43) | KDM4ELMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL9527768 | 0.80 | CYP2C9 (0.40) | KDM4ELMNAHTTSMN1; SMN2NPC1 | |
| SCHEMBL10406923 | 0.80 | CYP1A2 (0.40) | KDM4ELMNAHTTSMN1; SMN2GAA | |
| SCHEMBL9529150 | 0.75 | CYP4F2 (0.41) | KDM4ELMNAHTTSMN1; SMN2GAA | |
| SCHEMBL9532748 | 0.75 | POLB (0.46) | KDM4ELMNAHTTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |