Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530012 | 0.89 | KDM4E (0.42) | KDM4ETSHRLMNAL3MBTL1NPC1 | |
| SCHEMBL9532053 | 0.89 | NPC1 (0.43) | KDM4ETSHRLMNAL3MBTL1PAX8 | |
| SCHEMBL9529562 | 0.85 | KDM4E (0.42) | KDM4ELMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL23366565 | 0.82 | KDM4E (0.49) | KDM4ELMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL9529276 | 0.81 | ALDH1A1 (0.46) | KDM4ELMNANPC1AGTR1RAB9A | |
| SCHEMBL9532748 | 0.80 | POLB (0.46) | KDM4ETSHRLMNANPC1RAB9A | |
| SCHEMBL9527768 | 0.80 | CYP2C9 (0.40) | KDM4ETSHRLMNACTNNB1NPC1 | |
| SCHEMBL9529150 | 0.78 | CYP4F2 (0.41) | KDM4ELMNANAPRTP4HTML3MBTL1 | |
| SCHEMBL10407004 | 0.78 | TSHR (0.43) | TSHRRAB9ASMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL9528883 | 0.77 | NPC1 (0.43) | KDM4ETSHRLMNANAPRTP4HTM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2115166-A | — | — | None | — | — | JP | disclosed |
| EP-0560898-A4 | PHOTOCHROMIC NAPHTHOPYRANS | — | 1993-11-18 | — | — | EP | disclosed |
| EP-0560898-A1 | PHOTOCHROMIC NAPHTHOPYRANS. | PPG INDUSTRIES INC (US) | 1993-09-22 | — | — | EP | disclosed |
| JP-H02115166-A | PYRIDYLKETOXIME ETHER DERIVATIVE AND MEDICINE COMPOSITION CONTAINING THE SAME | KAKEN PHARMACEUT CO LTD | 1990-04-27 | — | — | JP | disclosed |