Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532029 | 0.89 | KDM4E (0.42) | KDM4ESMN1; SMN2LMNACYP1A2CYP3A4 | |
| SCHEMBL9532053 | 0.87 | NPC1 (0.43) | KDM4ESMN1; SMN2LMNAOPRK1CYP1A2 | |
| SCHEMBL9529562 | 0.83 | KDM4E (0.42) | KDM4EGAASMN1; SMN2LMNAHTT | |
| SCHEMBL9528779 | 0.80 | KDM4E (0.44) | KDM4EGAASMN1; SMN2LMNAMITF | |
| SCHEMBL9528175 | 0.80 | SMN1; SMN2 (0.40) | GAASMN1; SMN2LMNACYP1A2CYP3A4 | |
| SCHEMBL9532748 | 0.78 | POLB (0.46) | KDM4ESMN1; SMN2LMNACYP1A2CYP3A4 | |
| SCHEMBL23366565 | 0.77 | KDM4E (0.49) | KDM4EGAASMN1; SMN2LMNAHTT | |
| SCHEMBL9527691 | 0.77 | TSHR (0.45) | KDM4EGAASMN1; SMN2LMNACYP1A2 | |
| SCHEMBL9529276 | 0.76 | ALDH1A1 (0.46) | KDM4ELMNACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL9527768 | 0.75 | CYP2C9 (0.40) | KDM4ESMN1; SMN2LMNACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |