Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9532147 | 0.89 | CYP1A2 (0.44) | ABCB1POLBTSHRSMN1; SMN2HTR1A | |
| SCHEMBL9532132 | 0.86 | KMT2A (0.51) | ABCB1THRBHTR1ADRD2KDM4E | |
| SCHEMBL10407323 | 0.85 | ABCB1 (0.61) | ABCB1TSHRSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL9527826 | 0.85 | MAPK1 (0.53) | ABCB1POLBSMN1; SMN2RXFP1HTR1A | |
| SCHEMBL9528143 | 0.84 | CYP1A2 (0.42) | ABCB1POLBTSHRSMN1; SMN2HTR1A | |
| SCHEMBL9529759 | 0.83 | KMT2A (0.43) | ABCB1POLBTSHRSMN1; SMN2THRB | |
| SCHEMBL9529775 | 0.79 | TBXAS1 (0.50) | SGMS2ABCB1POLBTSHRSMN1; SMN2 | |
| SCHEMBL9529147 | 0.78 | NOTUM (0.44) | SGMS2SMN1; SMN2TP53ALDH1A1KMT2A | |
| SCHEMBL9528361 | 0.77 | ALDH1A1 (0.50) | ABCB1TSHRSMN1; SMN2HTR1ADRD2 | |
| SCHEMBL9528579 | 0.77 | ALDH1A1 (0.53) | ABCB1TSHRSMN1; SMN2HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |