Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530556 | 0.91 | MAPT (0.43) | KMT2AUSP2LMNANFKB1NFKB2 | |
| SCHEMBL9529148 | 0.89 | GLA (0.45) | KMT2AUSP2LMNANFKB1NFKB2 | |
| SCHEMBL9532132 | 0.88 | KMT2A (0.51) | KMT2AUSP2CYP2C9CYP11B1CYP11B2 | |
| SCHEMBL9529212 | 0.87 | MAPT (0.44) | KMT2ALMNANPC1POLBMAPT | |
| SCHEMBL9529772 | 0.83 | SGMS2 (0.47) | KMT2APOLBMAPTSMN1; SMN2TSHR | |
| SCHEMBL9532147 | 0.81 | CYP1A2 (0.44) | KMT2AUSP2LMNAPOLBMAPT | |
| SCHEMBL9529710 | 0.81 | RAB9A (0.44) | KMT2ALMNANPC1MAPTSMN1; SMN2 | |
| SCHEMBL10407323 | 0.81 | ABCB1 (0.61) | KMT2ASMN1; SMN2CYP1A2TSHRABCB1 | |
| SCHEMBL9531938 | 0.79 | TBXA2R (0.46) | KMT2ATSHRCYP11B1CYP11B2 | |
| SCHEMBL9528143 | 0.79 | CYP1A2 (0.42) | KMT2AUSP2LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0366006-B1 | PYRIDYLKETOXIME ETHER COMPOUND AND PHARMACEUTICAL COMPOSITION CONTAINING IT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-4971985-A | ANTIISCHEMIC AGENTS, CARDIOVASCULAR DISORDERS | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-11-20 | — | — | US | disclosed |
| EP-0366006-A1 | Pyridylketoxime ether compound and pharmaceutical composition containing it | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1990-05-02 | — | — | EP | disclosed |