Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.35 |
| ▸ | TPH1 | P17752 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | LGMN | Q99538 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RBP4 | P02753 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533258 | 0.84 | ALDH1A1 (0.38) | GAASIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9533260 | 0.84 | ALDH1A1 (0.38) | GAASIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL9424137 | 0.83 | GAA (0.36) | GAAACHEBCHELGMNMEN1 | |
| SCHEMBL9530210 | 0.79 | GRIN2D (0.32) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9059192 | 0.77 | SIGMAR1 (0.40) | SIGMAR1TPH1ACHELGMN | |
| SCHEMBL9424593 | 0.76 | ACHE (0.35) | GAATPH1ACHEBCHELGMN | |
| SCHEMBL9424008 | 0.69 | ALDH1A1 (0.40) | GAAMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL9424006 | 0.69 | ALDH1A1 (0.40) | GAAMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL9059644 | 0.68 | LGMN (0.43) | SIGMAR1BCHELGMNMEN1KMT2A | |
| SCHEMBL9532357 | 0.68 | ALDH1A1 (0.38) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385038-B1 | ORTHO-SUBSTITUTED PHENYL AMIDINE AND PHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM | The Boots Company PLC (GB) | 1993-06-02 | — | — | EP | disclosed |