Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530551 | 0.86 | RORC (0.44) | MAOAMAOBRORCSAE1UBA2 | |
| SCHEMBL9528131 | 0.86 | MAPT (0.45) | MAOAMAOBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL7896868 | 0.81 | NPY5R (0.50) | SMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL9838248 | 0.79 | NAMPT (0.57) | MAOAMAOBABCC9KCNJ11NAMPT | |
| SCHEMBL10453701 | 0.79 | ABCC9 (0.46) | SAE1UBA2SMN1; SMN2KMT2AABCC9 | |
| SCHEMBL10453762 | 0.78 | ABCC9 (0.45) | SAE1UBA2SMN1; SMN2KMT2AABCC9 | |
| SCHEMBL9531721 | 0.77 | MAPT (0.44) | CNR1SMN1; SMN2KMT2AALDH1A1LMNA | |
| SCHEMBL9529430 | 0.77 | TSHR (0.41) | RORCSAE1UBA2SMN1; SMN2KMT2A | |
| SCHEMBL9529425 | 0.77 | TSHR (0.41) | RORCSAE1UBA2SMN1; SMN2KMT2A | |
| SCHEMBL9530426 | 0.77 | TSHR (0.41) | RORCSAE1UBA2SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| US-4921939-A | GUANIDINE AND AMIDINE COMPOUNDS CONTAINING ACID GROUPS | UNIVERSITE CLAUDE BERNARD -LYON 1 (FR) | 1990-05-01 | — | — | US | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |
| EP-0241395-A2 | Sweeteners derived from n-phenylguanidinoacetic and n-phenylethananamidinacetic acids, and compositions containing such sweeteners | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1987-10-14 | — | — | EP | disclosed |