Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 4/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529172 | 0.82 | F2RL3 (0.39) | KDM4EPOLB | |
| SCHEMBL7508249 | 0.80 | KMO (0.39) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8474290 | 0.80 | ERN1 (0.41) | RXFP1KDM4EPOLBAMY1APDGFRB | |
| SCHEMBL8472019 | 0.76 | KDM4E (0.37) | KDM4EPOLBAMY1APDGFRBNPC1 | |
| SCHEMBL9529749 | 0.74 | GRM5 (0.33) | — | |
| SCHEMBL9532209 | 0.72 | AMY1A (0.39) | KDM4EPOLBAMY1APDGFRBERN1 | |
| SCHEMBL10340365 | 0.71 | AMY1A (0.50) | AMY1ARAB9AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8440309 | 0.69 | TRPV4 (0.36) | — | |
| SCHEMBL3394134 | 0.68 | PRKAB2 (0.45) | RXFP1KDM4EPOLBAMY1AALDH1A1 | |
| SCHEMBL3846093 | 0.67 | AMY1A (0.46) | RXFP1KDM4EAMY1APDGFRBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |