Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529749 | 0.88 | GRM5 (0.33) | F2RL3TP53GRM5 | |
| SCHEMBL7508249 | 0.85 | KMO (0.39) | KMO | |
| SCHEMBL9530449 | 0.82 | RXFP1 (0.40) | KDM4EPOLB | |
| SCHEMBL15814002 | 0.79 | F2RL3 (0.42) | F2RL3TP53MDM2KMOALPL | |
| SCHEMBL3800985 | 0.75 | F2RL3 (0.39) | F2RL3TP53MDM2KMOALPL | |
| SCHEMBL6913488 | 0.75 | ALDH1A1 (0.42) | F2RL3KMOALPLGRM5PDE10A | |
| SCHEMBL8440309 | 0.74 | TRPV4 (0.36) | — | |
| SCHEMBL26111723 | 0.71 | SCN4A (0.47) | F2RL3TP53MDM2KMOALPL | |
| SCHEMBL2344409 | 0.71 | PDE7A (0.38) | F2RL3GRM5PDE10AGABRG2GABRB3 | |
| SCHEMBL5050417 | 0.69 | F2RL3 (0.42) | F2RL3TP53MDM2KMOALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |
| WO-1992002509-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1992-02-20 | — | — | WO | disclosed |