Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.31 |
| ▸ | CA6 | P23280 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.30 |
| ▸ | KDR | P35968 | 2/20 | 0.30 |
| ▸ | MAP3K9 | P80192 | 2/20 | 0.30 |
| ▸ | MAP3K10 | Q02779 | 2/20 | 0.30 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.30 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9527460 | 0.83 | DRD1 (0.34) | LMNAKCNA3CA1CA2CA4 | |
| SCHEMBL9530865 | 0.78 | CA1 (0.50) | CA1CA2CA4CA6 | |
| SCHEMBL9526776 | 0.78 | ADORA3 (0.43) | ALDH1A1CA1CA2CA4CA6 | |
| SCHEMBL9526738 | 0.71 | DAO (0.41) | ALDH1A1LMNAHTTCA1CA2 | |
| SCHEMBL3903939 | 0.69 | KDM4E (0.47) | ALDH1A1LMNAHTTCA1CA2 | |
| SCHEMBL9526780 | 0.69 | DAO (0.41) | ALDH1A1LMNAHTTCA1CA2 | |
| SCHEMBL14963713 | 0.68 | MAOA (0.44) | ALDH1A1LMNACA1CA2CA4 | |
| SCHEMBL9527328 | 0.68 | CA1 (0.50) | CA1CA2CA4CA6ADORA3 | |
| SCHEMBL4374361 | 0.66 | CA1 (0.56) | ALDH1A1CA1CA2CA4CA6 | |
| SCHEMBL29370154 | 0.66 | CA1 (0.56) | ALDH1A1CA1CA2CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5185360-A | Antioxidants, free radical scavengers | UNIVERSITY OF BATH (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0404536-A1 | Indenoindole compounds I | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | EP | disclosed |
| WO-1990015800-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1990-12-27 | — | — | WO | disclosed |