SCHEMBL9531331

SCHEMBL9531331

C#Cc1cnc2sc(S(=O)(=O)CCCCCCC)nn2c1=O

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DCTPP1 Q9H773 1/20 0.32
SOAT1 P35610 9/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9530748 0.90 KDM4E (0.34) DCTPP1SOAT1KDM4E
SCHEMBL9535226 0.82 DCTPP1 (0.38) DCTPP1SOAT1
SCHEMBL9533205 0.81 SOAT1 (0.44) SOAT1
SCHEMBL9532673 0.81 SOAT1 (0.44) SOAT1
SCHEMBL9532215 0.81 ALDH1A1 (0.43) DCTPP1KDM4E
SCHEMBL9532500 0.81 ALDH1A1 (0.43) DCTPP1KDM4E
SCHEMBL9534429 0.78 CA12 (0.33) KDM4E
SCHEMBL9531838 0.76 MEN1 (0.33) SOAT1
SCHEMBL9535428 0.76 CA2 (0.40) SOAT1KDM4E
SCHEMBL9535424 0.76 KDM4E (0.43) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0284069-B1 Benzopyranopyridineacetic acid ester compounds and their pharmaceutical uses YOSHITOMI PHARMACEUTICAL (JP) 1993-12-08 EP claimed
EP-0238059-B1 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-06-16 EP disclosed
US-4971971-A FUNGICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-11-20 US disclosed
US-4866064-A AGRICULTURE HORTICULTURE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-09-12 US disclosed
EP-0282635-A2 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-09-21 EP disclosed
EP-0238059-A2 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-09-23 EP disclosed