SCHEMBL9530748

SCHEMBL9530748

CCCCCCCS(=O)(=O)c1nn2c(=O)c(C#N)cnc2s1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
SOAT1 P35610 9/20 0.31
DCTPP1 Q9H773 1/20 0.31
THRB P10828 1/20 0.31
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA3 P07451 1/20 0.30
CA4 P22748 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9531331 0.90 DCTPP1 (0.32) KDM4ESOAT1DCTPP1
SCHEMBL9535226 0.83 DCTPP1 (0.38) SOAT1DCTPP1THRB
SCHEMBL9533205 0.82 SOAT1 (0.44) MEN1GAAKMT2AALDH1A1HPGD
SCHEMBL9532673 0.82 SOAT1 (0.44) MEN1GAAKMT2AALDH1A1HPGD
SCHEMBL9532500 0.81 ALDH1A1 (0.43) KDM4EHSD17B10ALDH1A1HPGDDCTPP1
SCHEMBL9532215 0.81 ALDH1A1 (0.43) KDM4EHSD17B10ALDH1A1HPGDDCTPP1
SCHEMBL9533390 0.77 KDM4E (0.43) KDM4EMEN1HTTKMT2ATHRB
SCHEMBL9533394 0.77 CA2 (0.40) KDM4EMEN1GAAKMT2AALDH1A1
SCHEMBL9530755 0.77 MEN1 (0.33) KDM4EMEN1GAATSHRHTT
SCHEMBL9530746 0.75 HTT (0.47) KDM4EMEN1GAATSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0238059-B1 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-06-16 EP claimed
US-4971971-A FUNGICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-11-20 US claimed
EP-0282635-A2 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-09-21 EP claimed
EP-0238059-B1 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1993-06-16 EP disclosed
US-4971971-A FUNGICIDES KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-11-20 US disclosed
US-4866064-A AGRICULTURE HORTICULTURE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-09-12 US disclosed
EP-0282635-A2 5H-1,3,4-Thiadiazolo[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1988-09-21 EP disclosed
EP-0238059-A2 5H-1,3,4-Thiazole[3,2-a]pyrimidin-5-one derivatives and fungicidal compositions containing the same KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-09-23 EP disclosed