Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8495199 | 0.83 | CYP1A2 (0.63) | LOXL2MEN1KMT2AAPPFBP1 | |
| SCHEMBL7655222 | 0.83 | ACHE (0.60) | LOXL2MEN1KMT2APOLBAPP | |
| SCHEMBL322726 | 0.83 | ACHE (0.60) | LOXL2MEN1KMT2APOLBAPP | |
| SCHEMBL5552353 | 0.83 | CYP1A2 (0.53) | LOXL2MEN1KMT2ACYP19A1TSHR | |
| SCHEMBL8425628 | 0.83 | CYP1A2 (0.53) | MEN1KMT2AAPPFBP1MAPT | |
| SCHEMBL6632469 | 0.80 | MAPT (0.62) | LOXL2KMT2APOLBCYP19A1TSHR | |
| SCHEMBL6567516 | 0.80 | KCNJ1 (0.55) | MEN1KMT2APOLBAPPMAPT | |
| SCHEMBL6014000 | 0.80 | KCNJ1 (0.55) | MEN1KMT2APOLBAPPMAPT | |
| SCHEMBL8991472 | 0.78 | APP (0.64) | MEN1KMT2APOLBCYP19A1APP | |
| SCHEMBL8991479 | 0.78 | APP (0.64) | MEN1KMT2APOLBCYP19A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340064-B1 | BENZODIAZEPINES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE IN THERAPY | JOUVEINAL S.A. (FR) | 1993-03-17 | — | — | EP | disclosed |
| EP-0420716-A2 | Benzodiazepines, process and intermediates for their preparation and their therapeutic use | JOUVEINAL S.A. (FR) | 1991-04-03 | — | — | EP | disclosed |
| EP-0340064-A1 | Benzodiazepines, process and intermediates for their preparation and their use in therapy | JOUVEINAL S.A. (FR) | 1989-11-02 | — | — | EP | disclosed |
| US-4876251-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-10-24 | — | — | US | disclosed |