Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655222 | 0.83 | ACHE (0.60) | ALDH1A1MAPTLMNAMAOBMAOA | |
| SCHEMBL9531493 | 0.83 | LOXL2 (0.46) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL322726 | 0.83 | ACHE (0.60) | ALDH1A1MAPTLMNAMAOBMAOA | |
| SCHEMBL5552353 | 0.83 | CYP1A2 (0.53) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL8425628 | 0.83 | CYP1A2 (0.53) | CYP1A2CYP2C19ALDH1A1MAPTHTT | |
| SCHEMBL9588199 | 0.82 | HSD17B10 (0.50) | ALDH1A1MAPTHTTLMNAMAOB | |
| SCHEMBL6632469 | 0.80 | MAPT (0.62) | CYP1A2CYP2C9CYP2C19ALDH1A1MAPT | |
| SCHEMBL6567516 | 0.80 | KCNJ1 (0.55) | CYP1A2CYP2C9ALDH1A1MAPTHTT | |
| SCHEMBL6014000 | 0.80 | KCNJ1 (0.55) | CYP1A2CYP2C9ALDH1A1MAPTHTT | |
| SCHEMBL3366102 | 0.78 | MAOB (0.68) | CYP1A2CYP2C9CYP2C19MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869454-A | ANTICOAGULANTS | CORVAS INTERNATIONAL, INC. (US) | 1999-02-09 | — | — | US | disclosed |