Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | UBE2N | P61088 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552353 | 0.83 | CYP1A2 (0.53) | MAPTNPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL322726 | 0.80 | ACHE (0.60) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL8495199 | 0.80 | CYP1A2 (0.63) | MAPTNPC1RAB9AALDH1A1LOXL2 | |
| SCHEMBL9531493 | 0.80 | LOXL2 (0.46) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL7655222 | 0.80 | ACHE (0.60) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL8425628 | 0.79 | CYP1A2 (0.53) | MAPTALDH1A1L3MBTL1KMT2ACYP1A2 | |
| SCHEMBL8202649 | 0.78 | CYP3A4 (0.48) | MAPTNPC1RAB9AALDH1A1LOXL2 | |
| SCHEMBL6632472 | 0.77 | POLB (0.79) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL28018804 | 0.77 | MAPT (0.79) | MAPTPOLBNPC1RAB9AALDH1A1 | |
| SCHEMBL62411 | 0.77 | MAPT (1.00) | MAPTPOLBNPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104424-B1 | PROCESS FOR THE SYNTHESIS OF CARBAPENEM INTERMEDIATES | MERCK & CO INC (US) | 2004-04-07 | — | — | EP | claimed |