Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5552353 | 0.93 | CYP1A2 (0.53) | CYP1A2CYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL7655222 | 0.83 | ACHE (0.60) | ALDH1A1LMNAMAPTBCHEMAOB | |
| SCHEMBL27793265 | 0.83 | MAPT (0.53) | CYP1A2CYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL3846090 | 0.83 | MAPT (0.53) | CYP1A2CYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL322726 | 0.83 | ACHE (0.60) | ALDH1A1LMNAMAPTBCHEMAOB | |
| SCHEMBL9531493 | 0.83 | LOXL2 (0.46) | CYP1A2CYP2C19ALDH1A1MAPTCRHBP | |
| SCHEMBL8495199 | 0.83 | CYP1A2 (0.63) | CYP1A2CYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL6328580 | 0.81 | NFE2L2 (0.58) | CYP1A2CYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL9423244 | 0.81 | MAOA (0.51) | CYP1A2CYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL6632469 | 0.79 | MAPT (0.62) | CYP1A2CYP2C19ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4971962-A | ANTIBIOTICS FOR TREATMENT OF DISEASES RESISTANT TO PENICILLINS | LUCKY, LTD. (KR) | 1990-11-20 | — | — | US | claimed |
| US-4684724-A | ANTIBIOTICS, BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1987-08-04 | — | — | US | claimed |
| US-4556559-A | CLAVULANIC ACID ESTER, PENICILLIN | BEECHAM GROUP P.L.C. (GB) | 1985-12-03 | — | — | US | claimed |
| US-5856556-A | Azetidinone derivatives, a process for their preparation and their use as intermediates in the preparation of carbapenem antibiotics | SANKYO COMPANY, LIMITED (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0212404-A1 | 7-oxo-4-thia-1-azabicyclo [3.2.0] hept-2-ene derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |