Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 10/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nitroanilide SCHEMBL9528964 | 0.78 | RORC (0.36) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL9637992 | 0.74 | TXNRD1 (0.41) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| 2-Nitroaniline SCHEMBL9528959 | 0.74 | TXNRD1 (0.41) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL27257375 | 0.74 | RORC (0.39) | TXNRD1S1PR1HCRTR1HCRTR2 | |
| SCHEMBL9528691 | 0.74 | HCRTR1 (0.36) | TXNRD1HCRTR1HCRTR2 | |
| SCHEMBL6393197 | 0.61 | ALDH1A1 (0.49) | MAPK1 | |
| SCHEMBL31749121 | 0.60 | TXNRD1 (0.40) | TXNRD1S1PR4MAPTS1PR1MAPK1 | |
| SCHEMBL27273037 | 0.59 | MEN1 (0.41) | S1PR4MAPTS1PR1MAPK1RAB9A | |
| SCHEMBL24920801 | 0.59 | HCRTR1 (0.40) | MAPTMAPK1RAB9ANPSR1HCRTR1 | |
| SCHEMBL28020279 | 0.57 | NOTUM (0.44) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417875-B1 | 1-METHOXYPYRIMIDINYL-1H-1,2,4-TRIAZOLE-3-SULFONIC ACID NITROANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AGENTS WITH HERBICIDAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | claimed |
| EP-0417875-A2 | 1-Methoxypyrimidinyl-1H-1,2,4-triazole-3-sulfonic acid nitroanilides, process for their preparation and their use as agents with herbicidal activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-03-20 | — | — | EP | claimed |
| EP-0417875-B1 | 1-METHOXYPYRIMIDINYL-1H-1,2,4-TRIAZOLE-3-SULFONIC ACID NITROANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AGENTS WITH HERBICIDAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0417875-B1 | 1-METHOXYPYRIMIDINYL-1H-1,2,4-TRIAZOLE-3-SULFONIC ACID NITROANILIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AGENTS WITH HERBICIDAL ACTIVITY | SCHERING AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0417875-A2 | 1-Methoxypyrimidinyl-1H-1,2,4-triazole-3-sulfonic acid nitroanilides, process for their preparation and their use as agents with herbicidal activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-03-20 | — | — | EP | disclosed |
| EP-0417875-A2 | 1-Methoxypyrimidinyl-1H-1,2,4-triazole-3-sulfonic acid nitroanilides, process for their preparation and their use as agents with herbicidal activity | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-03-20 | — | — | EP | disclosed |