Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NFKBIA | P25963 | 3/20 | 0.39 |
| ▸ | RELA | Q04206 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Nitroaniline SCHEMBL9528959 | 0.81 | TXNRD1 (0.41) | TXNRD1MAPTMAPK1S1PR4S1PR1 | |
| Nitroanilide SCHEMBL9528964 | 0.77 | RORC (0.36) | TXNRD1TDP1MAPTMAPK1S1PR4 | |
| SCHEMBL9531761 | 0.74 | TXNRD1 (0.36) | TXNRD1MAPTMAPK1S1PR4S1PR1 | |
| SCHEMBL27257375 | 0.73 | RORC (0.39) | TXNRD1S1PR1 | |
| SCHEMBL9528691 | 0.73 | HCRTR1 (0.36) | TXNRD1 | |
| SCHEMBL9637967 | 0.72 | MYD88 (0.34) | TXNRD1ALDH1A1RELASLC40A1MEN1 | |
| SCHEMBL9537006 | 0.69 | DNMT1 (0.35) | TXNRD1ALDH1A1SLC40A1MEN1KMT2A | |
| SCHEMBL31749121 | 0.65 | TXNRD1 (0.40) | TXNRD1MAPTMAPK1S1PR4S1PR1 | |
| SCHEMBL8355135 | 0.63 | TSHR (0.54) | ALDH1A1NFKBIARELAMEN1KMT2A | |
| SCHEMBL4291285 | 0.62 | ALDH1A1 (0.68) | ALDH1A1NFKBIARELATDP1SLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5094682-A | 1-METHOXYPYRIMIDINYL-N-NITROPHENYL-1H-1,2,4-TRIAZOLE-3-SULPHONAMIDES AND THEIR USE AS HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | claimed |
| US-5094682-A | 1-METHOXYPYRIMIDINYL-N-NITROPHENYL-1H-1,2,4-TRIAZOLE-3-SULPHONAMIDES AND THEIR USE AS HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| US-5094682-A | 1-METHOXYPYRIMIDINYL-N-NITROPHENYL-1H-1,2,4-TRIAZOLE-3-SULPHONAMIDES AND THEIR USE AS HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| US-5094682-A | 1-METHOXYPYRIMIDINYL-N-NITROPHENYL-1H-1,2,4-TRIAZOLE-3-SULPHONAMIDES AND THEIR USE AS HERBICIDES | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |