Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 3/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350073 | 1.00 | PRKCA (0.38) | PRKCANAAADGKAGAAMAPT | |
| SCHEMBL13124951 | 1.00 | PRKCA (0.38) | PRKCANAAADGKAGAAMAPT | |
| SCHEMBL13124943 | 0.98 | GAA (0.36) | PRKCANAAADGKAGAAMAPT | |
| SCHEMBL10207669 | 0.87 | GAA (0.39) | GAALMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL14169233 | 0.86 | POLB (0.38) | — | |
| SCHEMBL16204253 | 0.83 | GAA (0.44) | GAALMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL10207678 | 0.81 | ALDH1A1 (0.38) | GAALMNAMEN1KMT2AL3MBTL1 | |
| SCHEMBL4353419 | 0.80 | GPR84 (0.41) | MEN1KMT2A | |
| SCHEMBL13124953 | 0.80 | GPR84 (0.41) | MEN1KMT2A | |
| SCHEMBL8948233 | 0.80 | GPR84 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238202-B1 | GLYCEROL DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC USE | Sankyo Company Limited (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5068340-A | Antagonist of platelet activating factor for treatment of asthma, inflammation or shock | SANKYO COMPANY, LIMITED (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0238202-A2 | Glycerol derivatives, their preparation and their therapeutic use | Sankyo Company Limited (JP) | 1987-09-23 | — | — | EP | disclosed |