Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529720 | 0.83 | SIGMAR1 (0.57) | SIGMAR1MEN1KMT2AHTR1DHTR1A | |
| SCHEMBL9531082 | 0.83 | SIGMAR1 (0.57) | SIGMAR1PPARGPPARAHTR1A | |
| SCHEMBL9530704 | 0.82 | SIGMAR1 (0.40) | SIGMAR1HTR1D | |
| SCHEMBL5539408 | 0.80 | SIGMAR1 (0.62) | SIGMAR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL7400519 | 0.79 | HTR1D (0.67) | SIGMAR1ALDH1A1HTR1DHTR1BHTR1A | |
| SCHEMBL11823875 | 0.79 | SIGMAR1 (0.60) | SIGMAR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL7306525 | 0.79 | SIGMAR1 (0.61) | SIGMAR1MEN1KMT2APARP1KDM4E | |
| Hydrochloric Acid SCHEMBL7404128 | 0.78 | HTR1D (0.66) | SIGMAR1ALDH1A1HTR1DHTR1BHTR1A | |
| SCHEMBL18936739 | 0.78 | SIGMAR1 (0.66) | SIGMAR1PPARGPPARAMEN1KMT2A | |
| SCHEMBL5536604 | 0.76 | SIGMAR1 (0.65) | SIGMAR1PPARGPPARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |