Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529720 | 0.83 | SIGMAR1 (0.57) | SIGMAR1HTR1DDRD2 | |
| SCHEMBL9531082 | 0.83 | SIGMAR1 (0.57) | SIGMAR1DRD2 | |
| SCHEMBL9532157 | 0.82 | SIGMAR1 (0.54) | SIGMAR1HTR1D | |
| SCHEMBL9533235 | 0.75 | HTR1D (0.44) | SIGMAR1HTR1DDRD2DRD4 | |
| SCHEMBL3318787 | 0.67 | DRD2 (0.46) | SIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL23735080 | 0.66 | KDM4E (0.39) | SIGMAR1DRD2DRD4 | |
| SCHEMBL20182439 | 0.66 | MEN1 (0.50) | QDPR | |
| Sulfuric Acid SCHEMBL17364146 | 0.65 | SIGMAR1 (0.41) | SIGMAR1DRD2DRD3DRD4 | |
| SCHEMBL466989 | 0.64 | SIGMAR1 (0.57) | SIGMAR1 | |
| SCHEMBL7303423 | 0.63 | QDPR (0.51) | SIGMAR1QDPRDRD2DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| EP-0515548-A4 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | — | 1993-03-10 | — | — | EP | disclosed |
| EP-0515548-A1 | IMIDAZOLE ANGIOTENSIN II ANTAGONISTS INCORPORATING A SUBSTITUTED BENZYL ELEMENT | MERCK & CO. INC. (US) | 1992-12-02 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |