Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.57 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9529720 | 0.86 | SIGMAR1 (0.57) | SIGMAR1HTR1ADRD2 | |
| SCHEMBL9532157 | 0.83 | SIGMAR1 (0.54) | SIGMAR1HTR1APPARGPPARA | |
| SCHEMBL9530704 | 0.83 | SIGMAR1 (0.40) | SIGMAR1DRD2 | |
| SCHEMBL9533235 | 0.75 | HTR1D (0.44) | SIGMAR1HTR1ADRD2 | |
| SCHEMBL6626009 | 0.74 | SIGMAR1 (0.65) | SIGMAR1HTR1ADRD2 | |
| SCHEMBL11938943 | 0.74 | SIGMAR1 (0.65) | SIGMAR1HTR1ADRD2PPARGPPARA | |
| SCHEMBL9531074 | 0.74 | SIGMAR1 (0.74) | SIGMAR1HTR1ADRD2PPARGPPARA | |
| SCHEMBL4493623 | 0.73 | SIGMAR1 (0.55) | SIGMAR1HTR1ADRD2PPARGPPARA | |
| SCHEMBL7108923 | 0.73 | SIGMAR1 (0.58) | SIGMAR1HTR1ADRD2 | |
| SCHEMBL7289482 | 0.73 | SIGMAR1 (0.67) | SIGMAR1HTR1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556342-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYOGYSZERKUTATO INTEZET K.V. (HU) | 1993-08-25 | — | — | EP | disclosed |
| WO-1992007854-A1 | NEW 1-AZABICYCLOALKANE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME | GYÓGYSZERKUTATÓ INTÉZET KV. (HU) | 1992-05-14 | — | — | WO | disclosed |