Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9531900 | 0.89 | MTNR1A (0.60) | MTNR1AMTNR1BDRD2GRIN2B | |
| SCHEMBL9532979 | 0.81 | MTNR1A (0.64) | MTNR1AMTNR1BDRD2DRD3HTR1D | |
| SCHEMBL9537304 | 0.80 | MTNR1A (0.58) | MTNR1AMTNR1BDRD2DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL9776461 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BDRD2DRD3HTR1A | |
| SCHEMBL10340388 | 0.79 | MTNR1A (0.67) | MTNR1AMTNR1BDRD2DRD3HTR1D | |
| SCHEMBL10340399 | 0.77 | MTNR1A (0.64) | MTNR1AMTNR1BDRD2DRD3 | |
| SCHEMBL9534218 | 0.75 | MTNR1A (0.52) | MTNR1AMTNR1BDRD2HTR2ADRD3 | |
| SCHEMBL11022976 | 0.75 | MTNR1A (0.61) | MTNR1AMTNR1BHTR1AHTR1DHTR1B | |
| SCHEMBL11036691 | 0.75 | MTNR1A (0.71) | MTNR1AMTNR1BDRD2DRD3 | |
| SCHEMBL10340372 | 0.74 | MTNR1A (0.74) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332968-B1 | 1,3,4,5-Tetrahydrobenz[c,d]indoles | BAYER AG (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0332968-A1 | 1,3,4,5-Tetrahydrobenz[c,d]indoles | BAYER AG (DE) | 1989-09-20 | — | — | EP | disclosed |