Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.58 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9776461 | 0.99 | MTNR1A (0.57) | MTNR1AMTNR1BHTR1DHTR1BHTR1A | |
| SCHEMBL9534218 | 0.86 | MTNR1A (0.52) | MTNR1AMTNR1BHTR1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL9776624 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BHTR1ADRD2DRD3 | |
| SCHEMBL9532979 | 0.82 | MTNR1A (0.64) | MTNR1AMTNR1BHTR1DHTR1BDRD2 | |
| SCHEMBL9537025 | 0.82 | MTNR1A (0.58) | MTNR1AMTNR1BHTR1DHTR1B | |
| SCHEMBL10340388 | 0.80 | MTNR1A (0.67) | MTNR1AMTNR1BHTR1DHTR1BDRD2 | |
| SCHEMBL9532235 | 0.80 | MTNR1A (0.53) | MTNR1AMTNR1BHTR1DHTR1BHTR1A | |
| SCHEMBL9776420 | 0.79 | HTR1A (0.53) | MTNR1AMTNR1BHTR1DHTR1BHTR1A | |
| Hydrochloric Acid SCHEMBL9532136 | 0.77 | MTNR1A (0.48) | MTNR1AMTNR1BHTR1DHTR1BHTR1A | |
| SCHEMBL9533189 | 0.77 | HTR1A (0.55) | MTNR1AMTNR1BHTR1DHTR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0332968-B1 | 1,3,4,5-Tetrahydrobenz[c,d]indoles | BAYER AG (DE) | 1993-06-02 | — | — | EP | disclosed |
| EP-0332968-A1 | 1,3,4,5-Tetrahydrobenz[c,d]indoles | BAYER AG (DE) | 1989-09-20 | — | — | EP | disclosed |