Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530548 | 0.80 | MEN1 (0.48) | NOS3NOS1HPGDALDH1A1TSHR | |
| SCHEMBL9530547 | 0.80 | MEN1 (0.48) | NOS3NOS1HPGDALDH1A1TSHR | |
| SCHEMBL9530153 | 0.78 | ALDH1A1 (0.42) | SCN9APOLBNOS3NOS1HPGD | |
| SCHEMBL10453700 | 0.77 | NOS3 (0.49) | NOS3NOS1HPGDGAAALDH1A1 | |
| SCHEMBL10453699 | 0.77 | NOS3 (0.49) | NOS3NOS1HPGDGAAALDH1A1 | |
| SCHEMBL9532610 | 0.75 | ALDH1A1 (0.42) | POLBHPGDGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL9527879 | 0.72 | IDO1 (0.47) | POLBNOS3NOS1HPGDMAPT | |
| SCHEMBL9529469 | 0.72 | NOS3 (0.53) | NOS3NOS1GAAALDH1A1MAPT | |
| SCHEMBL10453761 | 0.72 | NOS3 (0.43) | NOS3NOS1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9529688 | 0.72 | HPGD (0.70) | HPGDGAAALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |