Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530551 | 0.80 | RORC (0.44) | ALDH1A1LMNAMEN1KMT2ASAE1 | |
| SCHEMBL9530157 | 0.79 | GAA (0.49) | ALDH1A1ADRA2AADRA2BADRA2CL3MBTL1 | |
| SCHEMBL10453701 | 0.78 | ABCC9 (0.46) | ALDH1A1LMNAKDM4ERAB9AMEN1 | |
| SCHEMBL9532600 | 0.75 | SCN9A (0.41) | ALDH1A1LMNATRPM8RAB9APOLB | |
| SCHEMBL9530625 | 0.73 | MAOA (0.44) | ALDH1A1LMNAKMT2ASAE1UBA2 | |
| SCHEMBL9529457 | 0.73 | ABCC9 (0.46) | ALDH1A1LMNAKDM4ERAB9AMEN1 | |
| SCHEMBL8915586 | 0.73 | ABCC9 (0.46) | ALDH1A1LMNAKDM4ERAB9AMEN1 | |
| SCHEMBL10453762 | 0.72 | ABCC9 (0.45) | ALDH1A1LMNAKDM4ERAB9AMEN1 | |
| SCHEMBL10341391 | 0.71 | ABCC9 (0.45) | ALDH1A1LMNAKDM4ERAB9AMEN1 | |
| SCHEMBL10341392 | 0.71 | ABCC9 (0.45) | ALDH1A1LMNAKDM4ERAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0299533-B1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1993-04-07 | — | — | EP | disclosed |
| WO-1989000563-A1 | HIGH POTENCY SWEETENING AGENTS | THE NUTRASWEET COMPANY (US) | 1989-01-26 | — | — | WO | disclosed |
| EP-0299533-A2 | High potency sweetening agents | THE NUTRASWEET COMPANY (a Delaware corporation) (US) | 1989-01-18 | — | — | EP | disclosed |