Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13685090 | 0.97 | MAOA (0.48) | ALDH1A1MAOAMGLLHDAC8KMO | |
| SCHEMBL27775798 | 0.94 | HSD17B1 (0.43) | ALDH1A1MAOAMGLLHDAC8KMO | |
| SCHEMBL4582202 | 0.80 | NOTUM (0.54) | CYP3A4LMNAMAPTNOTUM | |
| SCHEMBL28128672 | 0.80 | HSD17B1 (0.34) | MAOAMGLLMEN1ESR1KMT2A | |
| SCHEMBL28167469 | 0.80 | HSD17B1 (0.39) | MAOAALOX5MEN1ESR1KMT2A | |
| SCHEMBL4486299 | 0.80 | AGXT (0.47) | MEN1ESR1KMT2ACYP3A4CYP2C9 | |
| SCHEMBL2094577 | 0.80 | PTPN5 (0.42) | ALDH1A1MEN1ESR1KMT2ACYP3A4 | |
| SCHEMBL2091157 | 0.80 | CYP1A2 (0.54) | ALDH1A1ALOX5MEN1ESR1KMT2A | |
| SCHEMBL19581748 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAOAMEN1ESR1KMT2A | |
| SCHEMBL2837498 | 0.80 | ALDH1A1 (0.53) | ALDH1A1MAOAMGLLKMOALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 976 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | FIBROGEN, INC. | 2024-01-04 | — | — | US | claimed |
| CN-116348450-A | Compounds, compositions and methods for histone lysine demethylase inhibition | 菲布罗根有限公司 | 2023-06-27 | — | — | CN | claimed |
| EP-3692101-B1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | ALFA INSTR S R L (IT) | 2022-01-12 | — | — | EP | claimed |
| CN-108368041-B | (R) -N- (adamantyl-2-yl) pyrrolidine-2-carboxamide derivatives for cosmetic use | 帝斯曼知识产权资产管理有限公司 | 2021-09-07 | — | — | CN | claimed |
| EP-3390359-B1 | (R)-N-(ADAMANTYL-2-YL)PYRROLIDINE-2-CARBOXAMIDE DERIVATIVES FOR COSMETIC USE | DSM IP ASSETS BV (NL) | 2021-01-27 | — | — | EP | claimed |
| EP-3692101-A1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | Alfa Instruments S.r.l. (IT) | 2020-08-12 | — | — | EP | claimed |
| US-10611869-B2 | Curable composition and cured product | AGC Inc. (JP) | 2020-04-07 | — | — | US | claimed |
| US-10470991-B2 | (R)-N-(adamantyl-2-yl)pyrrolidine-2-carboxamide derivatives for cosmetic use | DSM IP ASSETS B.V. (NL) | 2019-11-12 | — | — | US | claimed |
| US-20190218325-A1 | CURABLE COMPOSITION AND CURED PRODUCT | AGC Inc. (JP) | 2019-07-18 | — | — | US | claimed |
| WO-2019068935-A1 | BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES | ALFA INSTRUMENTS S.R.L. (IT) | 2019-04-11 | — | — | WO | claimed |
| EP-0003336-B1 | INSECTICIDAL PERHALOALKYLVINYLCYCLOPROPANECARBOXYLATES | FMC Corporation (US) | 1984-02-22 | — | — | EP | claimed |
| EP-0063374-B1 | SUBSTITUTED BIPHENYL COMPOUNDS | FMC Corporation (US) | 1984-02-22 | — | — | EP | claimed |
| EP-0063374-A1 | Substituted biphenyl compounds | FMC Corporation (US) | 1982-10-27 | — | — | EP | claimed |
| US-4329518-A | INSECTICIDES, ACARICIDES, MITICIDES | FMC CORPORATION (US) | 1982-05-11 | — | — | US | claimed |
| EP-0049977-A1 | Insecticidal (1,1'-biphenyl)-3-ylmethyl esters, their production and use and compositions containing them | FMC Corporation (US) | 1982-04-21 | — | — | EP | claimed |
| EP-0020685-A4 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. | FMC CORP (US) | 1981-07-16 | — | — | EP | claimed |
| EP-0001712-B1 | (1,1'-BIPHENYL)-3-YLMETHYL 3-(2,2-DIHALOETHENYL)-2,2-DIMETHYLCYCLOPROPANECARBOXYLATES, AGRICULTURAL COMPOSITIONS AND METHODS OF USE AND MANUFACTURE | FMC Corporation (US) | 1981-04-15 | — | — | EP | claimed |
| EP-0020685-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. | FMC CORP (US) | 1981-01-07 | — | — | EP | claimed |
| WO-1980001163-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED(1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS | FMC CORP (US) | 1980-06-12 | — | — | WO | claimed |
| EP-0003336-A2 | Insecticidal perhaloalkylvinylcyclopropanecarboxylates | FMC Corporation (US) | 1979-08-08 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10470991-B2 | (R)-N-(adamantyl-2-yl)pyrrolidine-2-carboxamide derivatives for cosmetic use | HSD3B1, HSD11B1, HSD17B1 | ALDH1A1 34/4885MAOA 514/4885MGLL 716/4885 |
| US-20240002344-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR HISTONE LYSINE DEMETHYLASE INHIBITION | KDM5C, KDM5B, KDM5A | ALDH1A1 2449/4885MAOA 1573/4885MGLL 1804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.