Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.39 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.39 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.39 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149752 | 0.83 | THRB (0.45) | MAOAMAOBALDH1A1TAAR1RAB9A | |
| SCHEMBL29716380 | 0.83 | THRB (0.45) | MAOAMAOBALDH1A1TAAR1RAB9A | |
| SCHEMBL10499879 | 0.82 | MAOA (0.46) | MAOAMAOBALDH1A1TAAR1RAB9A | |
| SCHEMBL20940182 | 0.81 | TAAR1 (0.44) | MAOAMAOBTAAR1RAB9ANPC1 | |
| SCHEMBL31612133 | 0.80 | IAPP (0.55) | MAOAMAOBALDH1A1LMNATAAR1 | |
| SCHEMBL1293 | 0.80 | IAPP (0.55) | MAOAMAOBALDH1A1LMNATAAR1 | |
| SCHEMBL27740606 | 0.80 | TAAR1 (0.45) | MAOAMAOBALDH1A1LMNATAAR1 | |
| SCHEMBL27449727 | 0.77 | TAAR1 (0.47) | TAAR1RAB9ANPC1PLAAT3PLAAT5 | |
| SCHEMBL14492582 | 0.77 | ALDH1A1 (0.51) | MAOAMAOBALDH1A1LMNATAAR1 | |
| SCHEMBL1821613 | 0.76 | TAAR1 (0.50) | LMNATAAR1RAB9ANPC1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539372-A1 | THERAPEUTIC AGENTS | The Boots Company PLC (GB) | 1993-05-05 | — | — | EP | disclosed |