Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.50 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612133 | 1.00 | IAPP (0.55) | IAPPALDH1A1LMNATAAR1PLAAT3 | |
| SCHEMBL14492582 | 0.96 | ALDH1A1 (0.51) | IAPPALDH1A1LMNATAAR1PLAAT3 | |
| Magnesium Chloride Anhydrous SCHEMBL28689545 | 0.94 | ALDH1A1 (0.50) | IAPPALDH1A1LMNATAAR1PLAAT3 | |
| SCHEMBL13235696 | 0.85 | IAPP (0.56) | IAPPALDH1A1LMNATAAR1SLC6A2 | |
| SCHEMBL7331092 | 0.83 | TAAR1 (0.54) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL6100122 | 0.83 | TAAR1 (0.54) | ALDH1A1TAAR1PLAAT3PLAAT5PLAAT2 | |
| Ethane SCHEMBL10497410 | 0.82 | FFAR1 (0.56) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8277219 | 0.82 | MAOA (0.54) | ALDH1A1LMNANPC1RAB9AMAOA | |
| SCHEMBL30323279 | 0.82 | IAPP (0.53) | IAPPALDH1A1LMNAPLAAT3PLAAT5 | |
| SCHEMBL455219 | 0.82 | FFAR1 (0.59) | TAAR1PLAAT3PLAAT5PLAAT2PLAAT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | STANFORD RES INST INT (US) | 2024-07-11 | — | — | US | disclosed |
| US-20230348369-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-11-02 | — | — | US | disclosed |
| US-20230016922-A1 | VISIBLE-LIGHT MEDIATED ORGANOPHOTOREDOX CATALYTIC DEUTERATION OF AROMATIC AND ALIPHATIC ALDEHYDES | NATIONAL INSTITUTES OF HEALTH | 2023-01-19 | — | — | US | disclosed |
| US-20220009876-A1 | METHOD FOR SYNTHESIZING D3 DOPAMINE RECEPTOR AGONISTS | POLYCORE THERAPEUTICS | 2022-01-13 | — | — | US | disclosed |
| WO-2021226276-A2 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| CN-108721283-A | Application of the thiazole in treating non-lymphocytic leukemia | 华东理工大学 | 2018-11-02 | — | — | CN | disclosed |
| US-9624182-B2 | Compounds as lysophosphatidic acid receptor antagonists | AMIRA PHARMACEUTICALS, INC. (US) | 2017-04-18 | — | — | US | disclosed |
| EP-2483252-B1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20150329502-A1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2015-11-19 | — | — | US | disclosed |
| US-9090573-B2 | Compounds as lysophosphatidic acid receptor antagonists | AMIRA PHARMACEUTICALS, INC. (US) | 2015-07-28 | — | — | US | disclosed |
| US-6548546-B2 | Administering a 2-hydroxy-4-oxo- or 4,6-dioxo-6-pheny-l or naphthyl- hex-2-enoic acid; viricides; AIDS/ARC | BRISTOL-MYERS SQUIBB COMPANY | 2003-04-15 | — | — | US | disclosed |
| EP-1275635-A1 | Calcium receptor-active compounds | NPS PHARMACEUTICALS, INC. (US) | 2003-01-15 | — | — | EP | disclosed |
| US-20020123527-A1 | HIV integrase inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-05 | — | — | US | disclosed |
| EP-1203761-A2 | Calcium receptor-active compounds | NPS PHARMACEUTICALS, INC. (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001098248-A2 | HIV INTEGRASE INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2001-12-27 | — | — | WO | disclosed |
| US-6211244-B1 | AROMATIC AMINES FOR COMPLEXING CALCIUM | NPS PHARMACEUTICALS, INC. | 2001-04-03 | — | — | US | disclosed |
| WO-1996012697-A9 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMA INC (US) | 2000-08-24 | — | — | WO | disclosed |
| EP-0787122-A2 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 1997-08-06 | — | — | EP | disclosed |
| WO-1996012697-A2 | CALCIUM RECEPTOR-ACTIVE COMPOUNDS | NPS PHARMACEUTICALS, INC. (US) | 1996-05-02 | — | — | WO | disclosed |
| US-5288726-A | Tetrahydrothienopyridine derivatives, furo and pyrrolo analogs thereof and their preparation and uses for inhibiting blood platelet aggregation | UBE INDUSTRIES LIMITED (JP) | 1994-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220009876-A1 | METHOD FOR SYNTHESIZING D3 DOPAMINE RECEPTOR AGONISTS | DRD3, DRD2, HTR3A | IAPP 1085/4885ALDH1A1 865/4885LMNA 4798/4885 |
| US-20230348369-A1 | NAMPT MODULATORS | NAMPT, NNT, NAPRT | IAPP 2144/4885ALDH1A1 982/4885LMNA 1650/4885 |
| US-20240228495-A1 | Tricyclic Inhibitors of Influenza Virus Endonuclease | RNASEH1, RNASEL, DNASE1 | IAPP 4369/4885ALDH1A1 802/4885LMNA 1328/4885 |
| US-20150329502-A1 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR4 | IAPP 1478/4885ALDH1A1 3726/4885LMNA 787/4885 |
| US-20020123527-A1 | HIV integrase inhibitors | POLM, NPC1, AP1M1 | IAPP 4799/4885ALDH1A1 1245/4885LMNA 978/4885 |
| US-20230016922-A1 | VISIBLE-LIGHT MEDIATED ORGANOPHOTOREDOX CATALYTIC DEUTERATION OF AROMATIC AND ALIPHATIC ALDEHYDES | AOX1, TDO2, TALDO1 | IAPP 4810/4885ALDH1A1 34/4885LMNA 3175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.