SCHEMBL9533348

SCHEMBL9533348

CS(=O)(=O)c1[nH]nc(-c2cc(S)c(Cl)cc2F)c1CCl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.33
SCN9A Q15858 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9529630 0.86 ATM (0.33) ATMSCN9A
SCHEMBL9529723 0.83 ATM (0.31) ATMSCN9A
SCHEMBL9532828 0.79 ACLY (0.32)
SCHEMBL9530495 0.77 NR1H4 (0.36) SCN9A
SCHEMBL9530440 0.75 LMNA (0.32) SCN9A
SCHEMBL9533344 0.67 SLC34A1 (0.30)
SCHEMBL26978765 0.64
SCHEMBL26656899 0.59 HTR5A (0.38)
SCHEMBL8570221 0.57 MEN1 (0.37)
SCHEMBL22372566 0.57 PTGS2 (0.32) SCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0542872-A1 HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES MONSANTO COMPANY (US) 1993-05-26 EP disclosed