Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.30 |
| ▸ | PPOX | P50336 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9530495 | 0.90 | NR1H4 (0.36) | TSHRKDM4EALDH1A1HPGDALPL | |
| SCHEMBL9529630 | 0.75 | ATM (0.33) | SCN9A | |
| SCHEMBL9533348 | 0.75 | ATM (0.33) | SCN9A | |
| SCHEMBL9696140 | 0.75 | LMNA (0.34) | LMNASMN1; SMN2TSHRMAPK1TDP1 | |
| SCHEMBL9532828 | 0.71 | ACLY (0.32) | — | |
| SCHEMBL9530433 | 0.71 | LMNA (0.34) | LMNASMN1; SMN2TSHRMAPK1HTT | |
| SCHEMBL8570497 | 0.69 | GAA (0.35) | LMNASMN1; SMN2TSHRMAPK1KDM4E | |
| SCHEMBL9534405 | 0.64 | KDM4E (0.37) | TSHRKDM4EALDH1A1HPGDPPOX | |
| SCHEMBL9529358 | 0.64 | KDM4E (0.35) | TSHRKDM4EALDH1A1HPGDSCN9A | |
| SCHEMBL9530763 | 0.62 | PPOX (0.38) | SMN1; SMN2ALDH1A1GAAPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542872-A1 | HERBICIDAL SUBSTITUTED ARYL ALKYLSULFONYL PYRAZOLES | MONSANTO COMPANY (US) | 1993-05-26 | — | — | EP | disclosed |