Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18499751 | 0.78 | MGLL (0.41) | MGLLMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL24628141 | 0.76 | MAOA (0.53) | HSD17B10ALDH1A1MAOAMAOB | |
| SCHEMBL611875 | 0.76 | HPGD (0.58) | MAPTHPGDALDH1A1MEN1KMT2A | |
| SCHEMBL19149930 | 0.74 | MAOA (0.39) | MGLLMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL18602960 | 0.74 | ALDH1A1 (0.39) | MGLLMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL11767314 | 0.72 | HPGD (0.41) | MGLLMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL24038373 | 0.72 | ACHE (0.48) | MAPTSMN1; SMN2ALDH1A1MAPK1MEN1 | |
| SCHEMBL10333922 | 0.72 | MGLL (0.55) | MGLLMAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL7190169 | 0.72 | NR1H2 (0.50) | MAPTHPGDSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL19274515 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0313458-B1 | IMIDAZO(2,1-B)BENZOTHIAZOLES AND THEIR ACID ADDITION SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-08-11 | — | — | EP | claimed |
| EP-0313458-A2 | Imidazo(2,1-b)benzothiazoles and their acid addition salts, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1989-04-26 | — | — | EP | claimed |
| US-20220386614-A1 | OXADIAZOLINE COMPOUND OR SALTS THEREOF, AGRICULTURAL AND HORTICULTURAL BACTERICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | NIHON NOHYAKU CO., LTD. (JP) | 2022-12-08 | — | — | US | disclosed |
| CN-111303150-B | High-efficiency narrow-half-peak-width aggregation state luminescent material | 苏州大学 | 2021-10-19 | — | — | CN | disclosed |
| CN-111303150-A | High-efficiency narrow-half-peak-width aggregation state luminescent material | 苏州大学 | 2020-06-19 | — | — | CN | disclosed |
| US-9758534-B2 | Organoaminosilanes and methods for making same | VERSUM MATERIALS US, LLC (US) | 2017-09-12 | — | — | US | disclosed |
| CN-104072484-B | Nitrogen-(4-(aromatic thiohydroxy)-1 hydrogen-indazole-3-base)-1-(heteroaromatic replacement) methylene imine compounds and pharmaceutically acceptable salt and its preparation method and application thereof | 渤海大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-102171287-A | Dispersed composition, polymerizable composition, light shielding color filter, solid-state imaging element, liquid crystal display device, wafer-level lens, and imaging unit | FUJIFILM CORP | 2011-08-31 | — | — | CN | disclosed |
| CN-1798538-A | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2006-07-05 | — | — | CN | disclosed |
| EP-0313458-B1 | IMIDAZO(2,1-B)BENZOTHIAZOLES AND THEIR ACID ADDITION SALTS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1993-08-11 | — | — | EP | disclosed |
| EP-0313458-A2 | Imidazo(2,1-b)benzothiazoles and their acid addition salts, process and intermediates for their preparation, their use as medicaments and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1989-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220386614-A1 | OXADIAZOLINE COMPOUND OR SALTS THEREOF, AGRICULTURAL AND HORTICULTURAL BACTERICIDE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | BROX, CYP51A1, TBCD | MGLL 1250/4885MAPT 2331/4885HPGD 2052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.