Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536745 | 0.81 | USP2 (0.37) | TSHRKMT2AMEN1TP53ALDH1A1 | |
| SCHEMBL9533763 | 0.70 | HTR1A (0.43) | HTR1ASLC6A4 | |
| SCHEMBL10145414 | 0.63 | LMNA (0.60) | LMNA | |
| SCHEMBL28242199 | 0.61 | LTA4H (0.63) | MAPTTSHRKMT2AMAOBTP53 | |
| SCHEMBL2222984 | 0.60 | SMN1; SMN2 (0.44) | SLC6A4KMT2AMEN1ALDH1A1 | |
| SCHEMBL11001305 | 0.60 | KDM4E (0.44) | KMT2AMEN1MAOAMAOBALDH1A1 | |
| SCHEMBL14204664 | 0.60 | ALDH1A1 (0.39) | MAPTTSHRALDH1A1MAPK1 | |
| SCHEMBL3103846 | 0.60 | SLC6A9 (0.56) | HTR1ASLC6A4KDM1AMAOAMAOB | |
| SCHEMBL5222434 | 0.59 | SLC6A2 (0.59) | SLC6A4ALDH1A1 | |
| SCHEMBL73643 | 0.59 | PNMT (0.54) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396620-B1 | AMINOMETHYL-CHROMAN AND -THIOCHROMAN COMPOUNDS | ABBOTT LABORATORIES (US) | 1993-08-11 | — | — | EP | claimed |