Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 11/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9538122 | 0.84 | SCN9A (0.50) | GHSRSCN9ASCN5A | |
| SCHEMBL9533421 | 0.81 | SCN9A (0.49) | GHSRSCN9ASCN5APTGS2MAPT | |
| SCHEMBL9535349 | 0.78 | SCN5A (0.46) | GHSRSCN9ASCN5A | |
| SCHEMBL9536053 | 0.73 | SCN9A (0.53) | GHSRSCN9ASCN5ATP53MAPT | |
| SCHEMBL9535220 | 0.71 | GHSR (0.51) | GHSRSCN9ASCN5AMAPT | |
| SCHEMBL12584905 | 0.71 | SCN9A (0.63) | SCN9ASCN5APTGS2MAPT | |
| SCHEMBL9535030 | 0.71 | GHSR (0.46) | GHSRSCN9ASCN5A | |
| SCHEMBL3637758 | 0.70 | GHSR (1.00) | GHSR | |
| SCHEMBL9537454 | 0.70 | GHSR (0.50) | GHSRPTGS2 | |
| SCHEMBL9535614 | 0.69 | TSHR (0.53) | SCN9ASCN5APTGS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |