Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9536170 | 0.91 | MAPT (0.52) | GHSRGPBAR1MEN1KMT2AALDH1A1 | |
| SCHEMBL9535755 | 0.88 | ALDH1A1 (0.52) | GHSRALDH1A1CYP3A4PTGS2CYP1A2 | |
| SCHEMBL9537105 | 0.85 | MAPT (0.56) | GPBAR1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL9534238 | 0.81 | POLB (0.45) | GHSRGPBAR1MEN1KMT2ACYP3A4 | |
| SCHEMBL9533383 | 0.79 | GPBAR1 (0.51) | GHSRGPBAR1MEN1KMT2ANPC1 | |
| SCHEMBL9533937 | 0.79 | ALDH1A1 (0.50) | GHSRMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9533918 | 0.76 | MAPT (0.64) | MEN1KMT2ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL10192035 | 0.73 | KMT2A (0.55) | MEN1KMT2ANPC1ALDH1A1CYP3A4 | |
| SCHEMBL9535442 | 0.71 | GPBAR1 (0.51) | GPBAR1MEN1KMT2ANPC1ALDH1A1 | |
| SCHEMBL9533943 | 0.70 | GHSR (0.54) | GHSRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573883-A1 | Utilization of 3 substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives against endoparasites new 3-substituted aryl-5-alkyl-isoxazole-4-carboxylic acid derivatives and process for their preparation | BAYER AG (DE) | 1993-12-15 | — | — | EP | disclosed |